The show was set on a United Galaxy Sanitation Patrol Cruiser, an interstellar garbage scow operating out of United Galaxies Space Station Perma One in the year 2226. Adam Quark, the main character, works to clean up trash in space by collecting "space baggies" with his trusted and highly unusual crew.
In its short run, Quark satirized such science fiction as Star Wars, 2001: A Space Odyssey, Lost in Space, Buck Rogers, and Flash Gordon. Three of the episodes were direct parodies of Star Trek episodes.